One form of epigenetic change known as DNA methylation is particularly understudied in this area.
"There's a large amount of evidence that a process known as DNA methylation is a key player in cancer development," Zhong said. "Today's next-generation sequencing techniques give us the data we need to close the gap in this area of research."
Zhong and her team will develop a suite of statistical models to broaden the understanding of how epigenetic patterns are established and maintained during normal development and under different environmental conditions.
Large amounts of epigenetic and genomic data are routinely collected, processed and stored. Statisticians like Zhong look for ways to make the data tell the story.
Congratulations to Dr. Zhong and her team on this new support for an important path of inquiry. These pursuits represent the very best of university research and the leading edge of scientific discovery.
Image: Wenxuan Zhong, associate professor in the Franklin College of Arts and Sciences department of statistics.